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INTRODUCTION POTRATE M ORAL SOLUTION is a combination of Potassium citrate and Magnesium citrate which belongs to the group of medicines called Urinary alkalizers and Saline laxatives respectively. It is used in the treatment of renal tubular acidosis with calcium stones and kidney stones (hyp...
POTRATE M ORAL SOLUTION is a combination of Potassium citrate and Magnesium citrate which belongs to the group of medicines called Urinary alkalizers and Saline laxatives respectively. It is used in the treatment of renal tubular acidosis with calcium stones and kidney stones (hypocitraturic calcium oxalate nephrolithiasis and uric acid lithiasis with or without calcium stones).
Renal tubular acidosis is a condition in which the kidneys do not remove acids from the blood into the urine as they usually should. Before taking POTRATE M ORAL SOLUTION, your doctor might want you to take certain blood tests and ECG to understand your existing condition.
POTRATE M ORAL SOLUTION is not recommended for use in patients with hyperkalemia (high potassium levels in the blood), gastrointestinal disease, peptic ulcer disease, urinary tract infection and kidney disease.
POTRATE M ORAL SOLUTION is not recommended for use in pregnant and breastfeeding women unless it is clearly advised by the doctor. Safety and effectiveness of POTRATE M ORAL SOLUTION in children has not been established yet. The most common side effects of taking POTRATE M ORAL SOLUTION are abdominal discomfort, nausea, vomiting and diarrhea.
Treats,
POTRATE M ORAL SOLUTION works by reducing the kidney stone formation. Potassium citrate and magnesium citrate, causes the metabolism of absorbed citrate producing an alkaline load. In addition to raising urinary pH and citrate, this also increases urinary potassium and magnesium. In certain patients, potassium citrate causes a transient reduction in urinary calcium. These changes produce urine that is less helpful to the crystallization of stone-forming salts.
Take POTRATE M ORAL SOLUTION as advised by your physician. Shake well before use. Use a measuring cup or spoon to properly measure a dose. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Stop taking POTRATE M ORAL SOLUTION and contact your doctor immediately if you experience any of the following side effects:
Drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom does not improve.
Try to take POTRATE M ORAL SOLUTION with or just after a meal or a snack. Stick to simple meals. Avoid eating oil rich, fried or spicy foods. Consult your doctor if the symptom does not improve.
Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-treat on your own and consult your doctor if the symptom does not improve.
POTRATE M ORAL SOLUTION should be used in pregnant woman only if considered clearly necessary. Consult your doctor before taking it.
POTRATE M ORAL SOLUTION should be used in breast-feeding woman only if considered clearly necessary. Consult your doctor before taking it.
POTRATE M ORAL SOLUTION is not recommended for use in patients with renal insufficiency. Consult your doctor before taking it.
Do not take POTRATE M ORAL SOLUTION if you are allergic to potassium citrate or magnesium citrate.
POTRATE M ORAL SOLUTION is not recommended for use in patients with severe myocardial damage or heart failure because it impairs the excretion of potassium. Consult your doctor before taking it.
Safety and effectiveness of POTRATE M ORAL SOLUTION have not been established yet in children. Consult your child’s doctor for advice.
POTRATE M ORAL SOLUTION is not recommended for use if you:
A. Drug - Drug interactions:
Before taking POTRATE M ORAL SOLUTION, inform your doctor if you are taking any of the following medicines:
Overdosage:
If you or anyone else accidentally take too much of POTRATE M ORAL SOLUTION, consult your doctor immediately or visit the nearby hospital. Overdosage symptom of POTRATE M ORAL SOLUTION is hyperkalemia (increased potassium in the blood).
| Drug | : | Potassium citrate, Magnesium citrate |
| Pharmacological Category | : | Urinary alkalizer , Saline laxative |
| Therapeutic Indication | : | Renal tubular acidosis (RTA) with calcium stones, Hypocitraturic calcium oxalate nephrolithiasis, Uric acid lithiasis |
| Dosage Forms | : | Oral solution, Oral suspension, Syrup, Tablet |
Q: What is POTRATE M ORAL SOLUTION used for?
A: POTRATE M ORAL SOLUTION is used in the treatment of renal tubular acidosis with calcium stones and kidney stones (hypocitraturic calcium oxalate nephrolithiasis and uric acid lithiasis with or without calcium stones).
Q: Can POTRATE M ORAL SOLUTION be used by pregnant women?
A: POTRATE M ORAL SOLUTION should be used in pregnant woman only if considered clearly necessary. Consult your doctor before taking this medicine if you are pregnant or planning to get pregnant.
Q: Is POTRATE M ORAL SOLUTION safe to use in patients with heart problems?
A: POTRATE M ORAL SOLUTION is not recommended for use in patients with severe myocardial damage or heart failure because it impairs the excretion of potassium. Consult your doctor before taking it.
Q: Can POTRATE M ORAL SOLUTION be used in children?
A: Safety and effectiveness of POTRATE M ORAL SOLUTION have not been established yet in children. Consult your child’s doctor for advice to select a suitable alternative therapy for your child to treat the specific condition.
Q: Does POTRATE M ORAL SOLUTION cause diarrhea?
A: Yes, POTRATE M ORAL SOLUTION may cause diarrhea in some individuals. To manage this effect, drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom does not improve.
1. Goodman Gilmans. Treatment of disorder of bowl motility and water flux. The Pharmacological Basis of Therapeutics. Twelfth Edition. 2011. Page –1331
2. B Ettinger, C Y Pak, J T Citron, C Thomas, B Adams-Huet, A Vangessel. Potassium-magnesium citrate is an effective prophylaxis against recurrent calcium oxalate nephrolithiasis. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. December 1997. [Accessed on 31st May 2022] https://pubmed.ncbi.nlm.nih.gov/9366314 /
3. Cipla Ltd . Ston1 oral solution (Potassium citrate + Magnesium citrate) Ciplamed. [Revised in April 2016] [Accessed on 31st May 2022] https://www.ciplamed.com/content/ston1-oral-solution
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 23 Feb 2023 | 06:00 PM(IST)