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INTRODUCTION AMPANEL 6 contains Perampanel which belongs to a group of medicines called anti epileptics which is used to treat epilepsy (repeated fits or seizures). Epilepsy is a disorder of central nervous system (neurological) where the activity of the brain becomes abnormal, causing seizure...
AMPANEL 6 contains Perampanel which belongs to a group of medicines called anti epileptics which is used to treat epilepsy (repeated fits or seizures). Epilepsy is a disorder of central nervous system (neurological) where the activity of the brain becomes abnormal, causing seizures or periods of unusual behavior, sensations, and sometimes loss of consciousness. It blocks a receptor in the brain known as the glutamate receptor. Glutamate is called a neurotransmitter that acts to excite nerve cells in the brain. AMPANEL 6 by affecting or blocking these glutamate receptors in the brain suppresses the abnormal and excessive activity of the nerve cells in the brain.
This medicine is used in association with other antiepileptic drugs to treat certain forms of epilepsy in people aged 12 years and older. Do not drive or operate any machines while taking this medicine as it may cause dizziness or sleepiness. It is not recommended for children below 12 years of age. Before taking AMPANEL 6, tell your doctor if you have kidney, liver problems, depression or suicidal thoughts and if you are pregnant or planning to become pregnant or breastfeeding. Your kidney function may need to be tested often while taking this medicine.
AMPANEL 6 works by blocking a receptor in the brain known as the glutamate receptor, thereby suppressing the abnormal and excessive activity of the nerve cells in the brain.
Always take AMPANEL 6 as directed your doctor. Swallow as a whole, do not crush or chew. It can be taken with or without food.
Dizziness:
Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.
Feeling sick (nausea) or indigestion:
Stick to simple meals and do not eat rich or spicy foods.
AMPANEL 6 is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
AMPANEL 6 should be used with caution for breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
Do not drive or operate any machines while taking this medicine as it may cause dizziness or sleepiness.
Consumption of alcohol is not recommended during treatment with AMPANEL 6.
AMPANEL 6 should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.
AMPANEL 6 should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.
Do not take if you are allergic (hypersensitive) to Perampanel or any ingredients in this medicine.
Tell your doctor if you had or have a condition such as:
Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:
| Drug | : | Perampanel |
| Pharmacological Category | : |
AMPA Glutamate Receptor Antagonist, Anticonvulsant |
| Therapeutic Indication | : |
Partial-onset seizures, Primary generalized tonic-clonic seizures |
| Dosage Forms | : | Tablet, Oral suspension |
Store below 20-25°C and keep out of reach of children.
Does AMPANEL 6 have abuse potential?
Yes, it has abuse potential in addition to its rewarding psychological or physiological effects. If a patient has a history of drug abuse then monitoring for this medicine abuse should be done.
What is epilepsy?
Epilepsy is a disorder of central nervous system (neurological) in which brain activity becomes abnormal, causes seizures or periods of unusual behavior, sensations, and sometimes loss of consciousness.
Does AMPANEL 6 cause weight gain?
Yes, it may cause weight gain. Talk to your doctor if you start gaining weight while taking this medicine.
1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page 1090-91.
2. Eisai Manufacturing Limited. Electronic Medicines Compendium (EMC); [Revised Nov, 2020] [Accessed on Oct 09, 2020] https://www.medicines.org.uk/emc/files/pil.7876.pdf
3. Eisai R&D Management Co., Ltd. 2012, U.S. Food & Drug Administration; [Revised Sep, 2020] [Accessed on Oct 09, 2020] https://www.fycompa.com/-/media/Files/Fycompa/Fycompa_Prescribing_Information.pdf
4. Jessica Greenwood and Jose Valdes. Perampanel (Fycompa): A Review of Clinical Efficacy and Safety in Epilepsy. Nov 2016, [Accessed on Oct 09, 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083075/