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INTRODUCTION NOVABLOCK 500MG INJECTION contains Tranexamic Acid which belongs to the group of medicines called Antifibrinolytics. It is used in the prevention and treatment of bleeding in conditions such as heavy menstrual bleeding in women, gastrointestinal bleeding (bleeding in digestive tra...
NOVABLOCK 500MG INJECTION contains Tranexamic Acid which belongs to the group of medicines called Antifibrinolytics. It is used in the prevention and treatment of bleeding in conditions such as heavy menstrual bleeding in women, gastrointestinal bleeding (bleeding in digestive tract, anywhere from the throat to rectum), bleeding due to thrombolytic therapy (medicine that is used to breakdown blood clots) and after having surgeries (such as ear, nose, throat, prostate gland, urinary tract, gynecological, abdominal or heart surgery) in adults and children above one year of age.
NOVABLOCK 500MG INJECTION is not recommended for use in patients with severe kidney impairment, blood clotting disorder or consumption coagulopathy (condition affecting the blood’s ability to clot and stop the bleeding) or history of seizures (fits). Your doctor may recommend you to take relevant tests to understand your existing condition.
Before receiving NOVABLOCK 500MG INJECTION, inform your doctor if you had or have blood in the urine, are at risk of having a blood clot, excessive clotting or bleeding throughout the body (disseminated intravascular coagulation).
NOVABLOCK 500MG INJECTION is not recommended for use in the first trimester of pregnancy and in breast-feeding women. It should be used with caution in pregnant women only if clearly advised by the doctor. NOVABLOCK 500MG INJECTION should be used with caution in elderly patients, especially in patients with the evidence of renal failure.
The most common side effects of receiving NOVABLOCK 500MG INJECTION are nausea or vomiting and diarrhea. Inform your doctor immediately if any of the side effect worsens.
Prevent and treats bleeding in children (aged above one) and adults in conditions such as:
NOVABLOCK 500MG INJECTION prevents bleeding by blocking the plasminogen from binding with fibrin which results in bleeding. As a result, it prevents and controls bleeding associated with various factors.
NOVABLOCK 500MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous injection. Your doctor will decide the correct dose, frequency and duration for you depending upon your age, body weight and disease condition.
Inform your doctor immediately if you experience any of the following side effects while receiving NOVABLOCK 500MG INJECTION:
Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods . Inform your doctor if the symptom gets worse.
Stick to simple meals while receiving this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Inform your doctor if the symptom does not improve.
NOVABLOCK 500MG INJECTION is not recommended for use in the first trimester of pregnancy. It should be used with caution in pregnant women only if considered clearly necessary. Women of childbearing potential should use effective contraception during treatment with this medicine. Consult your doctor before receiving NOVABLOCK 500MG INJECTION.
NOVABLOCK 500MG INJECTION is not recommended for use in breastfeeding women as it passes through breast milk. Consult your doctor for advice.
NOVABLOCK 500MG INJECTION is not recommended for use in patients with severe kidney impairment. It should be used with caution in patients with mild to moderate kidney impairment. Your doctor may adjust the dose depending upon the kidney function. Consult your doctor before receiving NOVABLOCK 500MG INJECTION.
NOVABLOCK 500MG INJECTION can be used with caution in patients with liver impairment. Consult your doctor before receiving NOVABLOCK 500MG INJECTION.
Do not receive NOVABLOCK 500MG INJECTION if you are allergic to Tranexamic acid or any other ingredients of this medicine.
NOVABLOCK 500MG INJECTION should be used with caution in children above 1 year of age. Your child’s doctor will adjust the dose based on the bodyweight of the child. Consult child’s doctor for advice before administration of NOVABLOCK 500MG INJECTION.
NOVABLOCK 500MG INJECTION should be used with caution in elderly patients, especially in patients with the evidence of renal failure. Consult your doctor before receiving NOVABLOCK 500MG INJECTION.
NOVABLOCK 500MG INJECTION is not recommended for use if you:
Before receiving NOVABLOCK 500MG INJECTION, inform your physician if you:
A. Drug-Drug interactions:
Before receiving NOVABLOCK 500MG INJECTION, inform your doctor if you have received or taking any of the following medicines:
Overdosage:
NOVABLOCK 500MG INJECTION will be given to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. However, if you experience any unusual symptoms contact your doctor immediately. Symptoms include dizziness, headache, low blood pressure and convulsions (fits).
| Drug | : | Tranexamic Acid |
| Pharmacological Category | : | Antifibrinolytics |
| Therapeutic Indication | : | Prevent and treats bleeding in certain conditions |
| Dosage Forms | : | Injection, Gel, Tablet |
Q: Can NOVABLOCK 500MG INJECTION be used in elderly patients?
A: NOVABLOCK 500MG INJECTION should be used with caution in elderly patients, especially in patients with the evidence of renal failure. Consult your doctor for advice before receiving NOVABLOCK 500MG INJECTION.
Q: Is NOVABLOCK 500MG INJECTION safe to use during pregnancy?
A: NOVABLOCK 500MG INJECTION is not recommended for use in the first trimester of pregnancy. It should be used with caution in pregnant women only if clearly advised by the doctor. Women of childbearing potential should use effective contraception during treatment with this medicine. Consult your doctor before receiving NOVABLOCK 500MG INJECTION.
Q: Can NOVABLOCK 500MG INJECTION be used in patients with impaired kidney function?
A: NOVABLOCK 500MG INJECTION is not recommended for use in patients with severe kidney impairment. It should be used with caution in patients with mild to moderate kidney impairment. Your doctor may adjust the dose depending upon the kidney function. Consult your doctor before receiving NOVABLOCK 500MG INJECTION.
Q: Does NOVABLOCK 500MG INJECTION cause nausea?
A: Yes, NOVABLOCK 500MG INJECTION may cause nausea in some individuals. To manage this effect, stick to simple meals while receiving this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Inform your doctor if the symptom does not improve.
Q: How NOVABLOCK 500MG INJECTION is administered?
A: NOVABLOCK 500MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous injection. It should not be injected into a muscle (intramuscularly). Your doctor will decide the correct dose, frequency and duration for you depending upon your age, body weight and disease condition.
1. KD. Tripathi. Drugs affecting blood and blood formation. Essentials of medical pharmacology. Eighth Edition. 2019. Page – 676.
2. John M. Chauncey, Jerald S. Wieters. Tranexamic Acid. NIH. National Library of Medicine, National center for biotechnology information. [Revised in January 2022] [Accessed on 14th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK532909/
3. Johnny Cai, Jessica Ribkoff, Sven Olson, Vikram Raghunathan, Hanny Al-Samkari, Thomas G. DeLoughery, and Joseph J. Shatzel. The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. December 2019 [Accessed on 14th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023891/
4. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in July 2022] [Accessed on 14th July 2022] https://www.medicines.org.uk/emc/files/pil.8953.pdf
5. Emcure Pharma UK Ltd. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on 14th July 2022] https://www.medicines.org.uk/emc/product/11894/smpc
6. Medochemie Ltd. Electronic Medicines Compendium (EMC). [Revised in May 2018] [Accessed on 14th July 2022] https://www.medicines.org.uk/emc/files/pil.3374.pdf
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 06 Mar 2023 | 09:16 AM(IST)