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INTRODUCTION DARIF 7.5MG TABLET contains Darifenacin which belongs to a group of medicines called Antimuscarinics. DARIF 7.5MG TABLET is used in adults to treat symptoms of overactive bladder conditions such as a sudden urge to rush to the toilet, needing to go to the toilet frequently and/or...
DARIF 7.5MG TABLET contains Darifenacin which belongs to a group of medicines called Antimuscarinics. DARIF 7.5MG TABLET is used in adults to treat symptoms of overactive bladder conditions such as a sudden urge to rush to the toilet, needing to go to the toilet frequently and/or not getting to the toilet in time and wetting yourself (urge incontinence).
DARIF 7.5MG TABLET is not recommended for use in patients allergic to Darifenacin. It is also not recommended for use in patients suffering from urinary retention (inability to empty your bladder), gastric retention, uncontrolled narrow-angle glaucoma (high pressure in the eyes), that is not being adequately treated), myasthenia gravis (disease characterized by unusual tiredness and weakness of selective muscles), severe ulcerative colitis/toxic megacolon (inflammatory bowel disease), and/or severe liver disease.
Before taking DARIF 7.5MG TABLET, inform your doctor if you have autonomic neuropathy (a condition of nerve damage), difficulties while passing urine, severe constipation, digestive motility disorder, obstructive gastrointestinal disorder (any obstruction of the passage of intestinal or gastric contents), mild to moderate liver problems, and/or kidney problems.
DARIF 7.5MG TABLET is not recommended for use during pregnancy and is advised to be used with caution in breastfeeding women.
DARIF 7.5MG TABLET is also not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor.
The most common side effects of taking DARIF 7.5MG TABLET are dry mouth, constipation, headache, abdominal pain, indigestion, nausea, and/or dry eyes. Consult your doctor if any of these symptoms worsens.
DARIF 7.5MG TABLET works by blocking certain receptors (M3 muscarinic acetylcholine receptors, responsible for bladder muscle contractions) which reduces the muscle spasms of the bladder and urinary tract thereby relaxing the bladder muscles that results in the prevention of urgent, frequent, or uncontrolled urination.
Tablet:
Take DARIF 7.5MG TABLET as advised by your physician. Swallow DARIF 7.5MG TABLET with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Stop taking DARIF 7.5MG TABLET and contact your doctor if you experience any of the following side effects:
Dry mouth:
Try to drink plenty of cold water. Sip on cold unsweetened drinks and use lip balm if your lips are dry. Try to brush your teeth twice a day and use mouthwash. Consult your doctor if the symptom gets worse.
Indigestion:
Try to have smaller and more frequent meals and eat and drink slowly. Try to reduce consumption of tea, coffee, cola or alcohol and lose weight if you are obese. Avoid smoking and don’t have rich, spicy or fatty foods. Consult your doctor if the symptom does not improve.
Headache:
If DARIF 7.5MG TABLET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Paracetamol is safe to be taken with DARIF 7.5MG TABLET. Headaches should usually go away after the first week of taking DARIF 7.5MG TABLET. If headaches last more than a week or severe, inform your doctor.
Constipation:
Try to eat more high-fiber foods such as fresh fruit, vegetables, cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate treatments for constipation.
Diarrhea:
Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to treat diarrhea and consult your doctor if the symptom gets worse.
Dizziness:
Try to rest and relax and get enough sleep. Try to avoid driving or operating any tools or machines while you are feeling dizzy. Limit your consumption of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom does not improve.
DARIF 7.5MG TABLET is not recommended for use during pregnancy. Consult your doctor before taking DARIF 7.5MG TABLET.
DARIF 7.5MG TABLET should be used with caution in breastfeeding women. Consult your doctor before taking DARIF 7.5MG TABLET.
Do not drive/operate machines if you experience dizziness, blurred vision, trouble while sleeping, and/or drowsiness after taking DARIF 7.5MG TABLET.
DARIF 7.5MG TABLET should be used with caution in patients with urinary tract infection, and/or other kidney problems. Consult your doctor before taking DARIF 7.5MG TABLET.
DARIF 7.5MG TABLET is not recommended for use in patients with severe liver disease. It should be used with caution in patients with mild to moderate liver problems. Consult your doctor before taking the medicine.
Do not take DARIF 7.5MG TABLET if you are allergic to Darifenacin, and/or any other ingredients of this medicine.
DARIF 7.5MG TABLET should be used with caution in patients with heart diseases. Consult your doctor before taking the medicine.
DARIF 7.5MG TABLET is not recommended for use if you:
Before taking DARIF 7.5MG TABLET, inform your doctor if you:
Use in Pediatrics:
DARIF 7.5MG TABLET is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before taking the medicine.
Use in Geriatrics:
DARIF 7.5MG TABLET should be used with caution in elderly patients (aged 65 years/above). Consult your doctor before taking the medicine.
A. Drug-Drug Interactions:
Before taking DARIF 7.5MG TABLET, inform your doctor, if you are taking any of the following medicine:
B. Drug-Food Interactions:
Consult your doctor before taking DARIF 7.5MG TABLET if you regularly take grapefruit juice which may interact with the medicine and alter its effect.
Overdosage:
If you or anyone else accidentally takes too much of DARIF 7.5MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are dry mouth, constipation, headache, indigestion, and/or nasal dryness.
| Drug | : | Darifenacin |
| Pharmacological Category | : | Antimuscarinics |
| Therapeutic Indication | : | Treat symptoms of overactive bladder |
| Dosage Forms | : | Tablet, Orally Disintegrating Tablet |
What DARIF 7.5MG TABLET is used for?
DARIF 7.5MG TABLET is used in adults to treat symptoms of overactive bladder conditions such as sudden urge to rush to the toilet, needing to go to the toilet frequently and/or not getting to the toilet in time and wetting yourself (urge incontinence).
How DARIF 7.5MG TABLET works?
DARIF 7.5MG TABLET works by blocking certain receptors (M3 muscarinic acetylcholine receptors, responsible for bladder muscle contractions) which reduces the muscle spasms of the bladder and urinary tract thereby relaxing the bladder muscles that results in the prevention of urgent, frequent, or uncontrolled urination.
What happens if you take more DARIF 7.5MG TABLET than your required dose?
If you or anyone else accidentally takes too much of DARIF 7.5MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are dry mouth, constipation, headache, indigestion and/or nasal dryness.
What are the common side effects of DARIF 7.5MG TABLET?
The most common side effects of taking DARIF 7.5MG TABLET are dry mouth, constipation, headache, abdominal pain, indigestion, nausea, and/or dry eyes. Consult your doctor if any of these symptoms worsens.
Is it safe to drive after taking DARIF 7.5MG TABLET?
Do not drive/operate machines if you experience dizziness, blurred vision, trouble while sleeping, and/or drowsiness after taking DARIF 7.5MG TABLET.
1. KD. Tripathi. Anticholinergic Drugs and Drugs Acting on Autonomic Ganglia. Essentials of medical pharmacology. Seventh edition. 2013. Page – 118.
2. Universidad de Valparaíso. Efficacy of Darifenacin and Physiotherapy for the Treatment of Overactive Bladder in Women. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in May 2016] [Accessed on 10th May 2022] https://clinicaltrials.gov/ct2/show/NCT02143570
3. Bethesda. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. NIH National Library of Medicine, National center for biotechnology information. July 2017 [Accessed on 10th May 2022] https://www.ncbi.nlm.nih.gov/books/NBK548798/#:~:text=Darifenacin%20
3. T Schneider, D Marschall-Kehrel, J U Hanisch, M C Michel. Do gender, age or lifestyle factors affect responses to antimuscarinic treatment in overactive bladder patients? NIH National Library of Medicine, National center for biotechnology information. August 2010 [Accessed on 10th May 2022] https://pubmed.ncbi.nlm.nih.gov/20500534/
4. DREHM Pharma GmbH. Electronic medicines compendium (EMC). [Revised in July 2021] [Accessed on 10th May 2022] https://www.medicines.org.uk/emc/files/pil.13251.pdf
Written By Dr. K .AZEEM HUSSAIN, B.D.S
Last updated on 17 Dec 2022 | 05:48 PM(IST)