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INTRODUCTION PRILOX CREAM is a combination of Lignocaine and Prilocaine which belongs to the group of medicines called Local Anesthetic agents. It is used to cause temporary numbness (loss of pain sensation) of the normal intact skin and genital mucosal membranes when applied topically....
PRILOX CREAM is a combination of Lignocaine and Prilocaine which belongs to the group of medicines called Local Anesthetic agents. It is used to cause temporary numbness (loss of pain sensation) of the normal intact skin and genital mucosal membranes when applied topically.
It is primarily used to abolish pain signals prior to surgical and diagnostic procedures on the skin and genital areas (such as during insertion of needles or catheters, during certain painful vaccinations (such as MMR, flu, hepatitis, DPT), during minor surgeries of genital areas (such as removal of foreskin around the penis) and during laser treatment or other cosmetic procedures involving the skin surface).
PRILOX CREAM can also be used to temporarily numb skin before injecting an anesthetic solution and can be used to abolish pain signals while removing dead and damaged skin/cells among patients with leg ulcers. It also provides relief from the symptoms of atopic dermatitis (red, itchy skin) in adults.
PRILOX CREAM is suitable for use both in adults and in children (including infants and newborns). It should be used only under careful medical supervision. It will be applied to you only by a doctor or nurse at skin surfaces where loss of sensation is required.
Before PRILOX CREAM is applied onto your skin, inform your doctor if you have any genetic disorders (like G6PD deficiency) or blood problems (such as methemoglobinemia). You must also inform your doctor if you are pregnant or breastfeeding before this medicine is given to you as a precaution.
PRILOX CREAM is not suitable for use in patients with problems in ear drum. The most common side effects of using PRILOX CREAM are paleness, redness, swelling, mild burning sensation, itching or warmth at the treated area. Consult your doctor if it bothers you.
Used as topical anesthesia prior to surgical and diagnostic procedures to:
PRILOX CREAM is a local anesthetic medication. When applied topically, it blocks the flow of certain ions (sodium ions) through the nerves that causes pain sensation. As a result, it limits the transfer of pain signals from the peripheral part of the body (i.e., face, hands, legs, abdomen, pelvis, genitals or where the medicine has been applied) to the brain which ultimately leads to loss of sensation.
PRILOX CREAM should be used only under careful medical supervision. It is strictly for external use only. It will be applied to you only by a doctor or nurse at skin surfaces where loss of sensation is required.
Avoid accidental contact of this medicine with your eyes, nose, ears, mouth or anus and with damaged skin surfaces including minor cuts on the skin.
Your doctor will decide the correct dose for you depending upon your age, body weight, health condition and sites where numbness is required in the body.
Contact your doctor immediately if you experience any of the following side effects after using PRILOX CREAM:
Application site reactions:
This side effect is usually temporary and disappears after few minutes of application. Additionally, you can also follow a few measures that can prevent your skin condition from worsening. This includes, avoiding hot showers or using irritant soaps or cosmetics (such as chemical peelings) on the treated skin surface. Do not use vaginal wash or other solutions if your genital areas are treated. Consult your doctor if this symptom is persistent for a prolonged period or worsens.
PRILOX CREAM should be used with caution among pregnant women. Therefore, inform your doctor before application.
PRILOX CREAM should be used with caution among breastfeeding women. Therefore, inform your doctor before application.
PRILOX CREAM is unlikely to affect your ability for driving or handling heavy tools or machines.
Talk to your doctor before PRILOX CREAM is applied onto your skin, if you are allergic to lignocaine, prilocaine or to any other local anesthetic agents (such as bupivacaine).
PRILOX CREAM is not recommended for use if you:
Before PRILOX CREAM is applied onto your skin, inform your physician if you:
Use in pediatrics:
PRILOX CREAM can be used in children and adolescents (aged below 18 years) if prescribed by the physician. However, it should not be used on the genital areas of children aged below 12 years. Therefore, consult your doctor for advice before application.
Use in geriatrics:
PRILOX CREAM should be used with caution in the elderly patients. Therefore, consult your doctor for advice before application.
A. Drug-Drug interactions:
Before PRILOX CREAM is applied onto your skin, inform your doctor if you are taking any of the following medicines such as:
Overdosage:
PRILOX CREAM will be applied to you only by a doctor or a nurse onto the skin. Therefore, it is unlikely to receive an overdose. However, if you experience any unusual side effects such as dizziness, blurred vision, tingling sensation around the mouth, numbness of tongue, abnormal taste or ringing in the ears, contact your doctor or visit the nearby hospital immediately.
| Drug | : | Lignocaine, Prilocaine |
| Pharmacological Category | : | Voltage Gated Sodium Channel Blockers |
| Therapeutic Indication | : | Local anesthesia |
| Dosage Forms | : | Gel, Cream, Spray |
Can PRILOX CREAM be used on the face?
PRILOX CREAM is used on the facial skin surface to cause temporary numbness prior to laser treatment/cosmetic surgeries (such as removal of skin tags, moles, scars, etc.).
Can PRILOX CREAM be used for cosmetic procedures?
PRILOX CREAM is used for performing minor cosmetic procedures such as laser hair removal, microblading, micro-needling, lip/facial fillers, Botox filler, PRP injection etc. It is also used to numb skin before tattooing.
Is PRILOX CREAM safe for use in pregnant women?
PRILOX CREAM should be used with caution among pregnant women. Therefore, inform your doctor before application.
How long will it take for PRILOX CREAM to induce numbness?
It may take around 3-5 minutes for PRILOX CREAM to create numbness. However, this period may vary from person-to-person based on the dose and amount of PRILOX CREAM that is administered.
How long does the effects of PRILOX CREAM lasts long in the body?
The effects of PRILOX CREAM may last between 15-30 minutes after application. However, the recovery period may vary from person-to-person based on the dose and amount of the PRILOX CREAM applied.
What is the use of PRILOX CREAM?
PRILOX CREAM is used to cause temporary numbness (loss of pain sensation) of the normal intact skin and genital mucosal membranes when applied topically. It is primarily used to abolish pain signals prior to surgical and diagnostic procedures on the skin and genital areas.
How to use PRILOX CREAM?
PRILOX CREAM should be used only under careful medical supervision. It is strictly for external use only. It will be applied to you only by a doctor or nurse at skin surfaces where loss of sensation is required.
Can PRILOX CREAM be used in children?
PRILOX CREAM can be used in children and adolescents (aged below 18 years) if prescribed by the physician. However, it should not be used on the genital areas of children aged below 12 years. Therefore, consult your doctor for advice before application.
Can PRILOX CREAM be used in infants?
PRILOX CREAM can be used in newborns and infants (aged between 0-11 months) if prescribed by the doctor. It is not recommended for use in preterm infants. Therefore, consult your doctor for advice.
What if I have accidental exposure of PRILOX CREAM to the eye?
Use lukewarm water to gently wash the outer surface of the eye in case of accidental contact with PRILOX CREAM. If the discomfort in the eye persists, contact your doctor, or visit a nearby hospital immediately.
What are the side effects of PRILOX CREAM?
The most common side effects of using PRILOX CREAM are paleness, redness, swelling, mild burning sensation, itching or warmth at the treated area. Consult your doctor if it bothers you.
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6. Akorn pharmaceuticals. U.S. National Library of Medicine. lidocaine and prilocaine cream. [Revised in March 2022] [Accessed on 14th December 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=9378d186-5b25-49bc-8563-a659fa1194c2&type=display
7. Aspen Pharma UK Limited. Emla Cream. [Accessed on 14th December 2022] https://www.emla.co.uk/
8. Central Drugs Standard Control Organization. Lidocaine 2%+Prilocaine 2.5% w/w cream. May 1999. [Accessed on 14th December 2022] https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalNewDrugs/dciApprovedfdc.pdf
Written By Srilekha. R, B.Pharm
Last updated on 17 Dec 2022 | 06:18 PM(IST)