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INTRODUCTION ORNI 500MG TABLET contains Ornidazole which belongs to the group of medicines called Antiprotozoals. It is used to treat infections that are caused by anaerobic bacteria (bacteria that do not use oxygen) or amoeba (single-celled parasites). Infections include certain types of vagi...
ORNI 500MG TABLET contains Ornidazole which belongs to the group of medicines called Antiprotozoals. It is used to treat infections that are caused by anaerobic bacteria (bacteria that do not use oxygen) or amoeba (single-celled parasites). Infections include certain types of vaginal, urinary tract and intestinal infections or some specific infections in the body. It is also used as prophylaxis during surgery to prevent these types of infections.
Before taking ORNI 500MG TABLET, inform your doctor if you have epilepsy, multiple sclerosis (disease which affects the central nervous system), liver disease or if you are undergoing hemodialysis. Your doctor might advise you to take certain blood tests prior to treatment with ORNI 500MG TABLET to understand the existing condition and to safely use this medicine.
ORNI 500MG TABLET is not recommended for use in pregnant women unless clearly advised by the doctor and it should be used with caution in breast-feeding women. ORNI 500MG TABLET can be used in children and your child’s doctor may adjust the dose depending upon child’s body weight and type of the infection.
While taking this medicine you may experience side effects such as nausea, vomiting, diarrhea, dry mouth and loss of appetite. Consult your doctor if any of the side effects worsen.
ORNI 500MG TABLET contains ornidazole which is an antiprotozoal agent that kills parasites and bacteria (that lives in the absence of oxygen) by generating harmful molecule which damages the DNA of the parasites and bacteria, thus helps to treat and prevent certain types of infections.
Take ORNI 500MG TABLET as advised by your doctor. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Avoid taking this medicine on empty stomach. Your doctor will decide the correct dose and duration of ORNI 500MG TABLET for you depending on your age, body weight and disease condition.
Stop taking ORNI 500MG TABLET and contact your physician immediately if you experience any of the following side effects:
Nausea or vomiting:
Stick to simple meals while taking this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.
Diarrhea:
Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Try to avoid taking any medicine on your own to treat diarrhea and consult your doctor if the symptom gets worse.
Dry Mouth:
Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.
Loss of appetite:
Eat when you feel hungry. Eat smaller meals frequently than usual. Snack only when you're hungry. Eat a nutritious snack which is rich in calories and protein, such as dried fruits and nuts. Consult your doctor if the symptom does not improve.
ORNI 500MG TABLET is not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking it.
ORNI 500MG TABLET should be used with caution in breastfeeding women as it is not known if it passes in the breastmilk. Consult your doctor before taking it.
Do not drive or operate any machines if you experience dizziness, drowsiness or light headedness after taking ORNI 500MG TABLET.
Avoid consumption of alcohol while taking ORNI 500MG TABLET and for at least 3 days after finishing the treatment.
ORNI 500MG TABLET should be used with caution in patients undergoing haemodialysis. Your doctor may advice you to take additional dose because this medicine is removed by haemodialysis. Consult your doctor before taking it.
ORNI 500MG TABLET should be taken with caution in patients with liver disease. Consult your doctor before taking it.
Do not take ORNI 500MG TABLET if you are allergic to Ornidazole, nitroimidazole derivatives (such as metronidazole) or any of the other ingredients of this medicine.
Before taking ORNI 500MG TABLET, inform your doctor if you:
Use in pediatrics:
ORNI 500MG TABLET can be used in children and your child’s doctor may adjust the dose depending upon child’s body weight and type of the infection. Consult your child’s doctor for advice.
A. Drug-Drug interactions:
Before taking ORNI 500MG TABLET, inform your doctor if you are taking any of the following medicines:
Overdosage
If you or anyone else accidentally takes too much of ORNI 500MG TABLET, consult your doctor immediately or visit the nearby hospital.
| Drug | : | Ornidazole |
| Pharmacological Category | : | Antiprotozoals |
| Therapeutic Indication | : | Certain types of vaginal, urinary tract and intestinal infections; Prevent infections during surgery |
| Dosage Forms | : | Tablet, Gel, Injection, Infusion, Suspension |
What if I forget to take a dose of ORNI 500MG TABLET?
If you forget to take a dose of ORNI 500MG TABLET, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the next scheduled dose at the prescribed time. Do not double the dose to make up for the missed dose as this may increase the chances of developing side effects.
Is it safe to use ORNI 500MG TABLET during pregnancy?
ORNI 500MG TABLET is not recommended for use in pregnant women unless clearly advised by the doctor. Consult your doctor before taking ORNI 500MG TABLET if you are pregnant or planning to get pregnant.
Does ORNI 500MG TABLET cause diarrhea?
Yes, ORNI 500MG TABLET may cause diarrhea in some individuals. To manage this effect, drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Try to avoid taking any medicine on your own to treat diarrhea and consult your doctor if the symptom gets worse.
When to seek medical emergency while taking ORNI 500MG TABLET?
Stop taking ORNI 500MG TABLET and contact your physician immediately if you experience rigidity, poor coordination, seizures, loss of consciousness, and allergic reactions (signs include severe skin rash, itching, hives, swelling of the face, lips, mouth, throat, hands, feet or ankles, difficulty in swallowing or breathing).
Can I drink alcohol while taking ORNI 500MG TABLET?
No, avoid consumption of alcohol while taking ORNI 500MG TABLET and for at least 3 days after finishing the treatment with this medicine, as it worsens the side effects. Consult your doctor for advice before taking ORNI 500MG TABLET.
1. KD. Tripathi. Corticosteroids. Drugs Essentials of medical pharmacology. Seventh edition. 2013. Page – 289.
2. O.Kurt, N.Girginkardesler, I.C.Balcioglu, A.Ozbilgin, U.Z.Ok. A comparison of metronidazole and single-dose ornidazole for the treatment of dientamoebiasis. Journal of Clinical Microbiology and Infection. June 2008. [Accessed on 20th August 2022] https://www.sciencedirect.com/science/article/pii/S1198743X14619583
3. Yehouda Marcus, Noam Tal, Mordechai Ronen, Raanan Carmieli, Michael Gurevitz. The drug ornidazole inhibits photosynthesis in a different mechanism described for protozoa and anaerobic bacteria. NIH National Library for medicine, National centre for biotechnology information. Pubmed.gov. December 2016. [Accessed on 20th August 2022] https://pubmed.ncbi.nlm.nih.gov/27647935/
4. Teva Pharma Limited. Arrow tablet (Ornidazole). [Revised in May 2017] [Accessed on 20th August 2022] https://www.medsafe.govt.nz/Consumers/cmi/a/arrowornidazole.pdf
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 27 Sep 2022 | 09:20 AM(IST)