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INTRODUCTION AB NEXT GEL is a combination of Adapalene and Benzoyl peroxide which belongs to the group of medicines called Antiacne agents. It is used in the treatment of acne. Acne vulgaris (commonly known as acne) is an inflammatory skin condition that occurs when the ha...
AB NEXT GEL is a combination of Adapalene and Benzoyl peroxide which belongs to the group of medicines called Antiacne agents. It is used in the treatment of acne.
Acne vulgaris (commonly known as acne) is an inflammatory skin condition that occurs when the hair follicles present in the skin are clogged with excess oil and/or dead skin cells. It can also be aggravated by few bacteria (such as Propionibacterium acnes) and is highly common among on the teenagers and the young adults.
It primarily affects the face, upper arms, trunk or back and is often characterized by pus-filled pimples, red bumps with inflammatory and non-inflammatory lesions. AB NEXT GEL is suitable for use both in adults and in children (aged 9 years or older).
Apply a thin layer of AB NEXT GEL on the affected skin areas. Avoid contact of this medicine with your eyes, mouth, ears, nose or with open wounds. You must also protect your skin against sun light and against other light sources (such as UV lamps).
Do not use AB NEXT GEL if you are pregnant, think you may be pregnant or planning to have a baby. AB NEXT GEL can be used in breastfeeding women if required. The most common side effects of using AB NEXT GEL are dry skin, mild burning sensation and skin irritation, redness or scaling. Consult your doctor if they trouble you.
It is used in adults, children and in adolescents (aged 9 years or older) to:
AB NEXT GEL is a combination of two medicines namely, adapalene and benzoyl peroxide.
Adapalene is a topical retinoid (a type of vitamin A). It modulates the skin cell cycle and prevents the accumulation of excess sebum (natural oil produced by the skin) and dead skin cells on the hair follicles of the skin. It also reduces inflammation on the skin.
Benzoyl peroxide is a keratolytic agent with antimicrobial properties. It improves skin’s tendency to exfoliate the dead skin cells naturally. It also reduces the number of acne-causing bacteria on the skin which can reduce the further spread of acne.
Collectively, they unclog the hair follicles of the skin and exfoliates dead skin cells which reduces acne breakouts.
Apply a thin layer of this medicine on the affected skin areas or as directed by the physician . It is for topical use only. Wash your hands before and after application.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.
Avoid contact of AB NEXT GEL with your eyes, mouth, ears, nose, hair or with open wounds (cuts, scrapes or sunburn).
Stop using AB NEXT GEL and consult your doctor immediately if you experience:
Skin redness and irritation:
Place an icepack on the affected skin areas to ease the irritation. Avoid using harsh chemicals or soaps on the affected areas. Wear protective loose-fitting clothes while going outdoors. Regularly moisturize your skin. Avoid exposing your skin towards direct sunlight. If the condition did not improve, contact your doctor.
AB NEXT GEL is not recommended for use in pregnant women. Therefore, inform your doctor before using this medicine if you are pregnant, think you may be pregnant or planning to have a baby. If you became pregnant while using this medicine, stop using it and contact your doctor immediately.
AB NEXT GEL can be used in breastfeeding women. However, do not apply this medicine on your chest to avoid exposing this medicine to the nursing infant.
Talk to your doctor if you are allergic to Adapalene or Benzoyl peroxide.
AB NEXT GEL is not recommended for use if you:
Use in Pediatrics:
AB NEXT GEL can be used in children and adolescents (aged 9 years or older) if advised by the physician. Therefore, consult your doctor before using it.
A. Drug-Drug interactions:
Before using AB NEXT GEL, inform your doctor if you are using any of the following:
Overdosage:
If you or anyone else applied excessive amount of AB NEXT GEL, rinse your skin with plenty of cold water. If irritation persists, consult your doctor.
| Drug | : | Adapalene, Benzoyl peroxide |
| Pharmacological Category | : | Retinoid-like compounds, Topical Antibiotics |
| Therapeutic Indication | : | Acne vulgaris |
| Dosage Forms | : | Topical Gel |
Will AB NEXT GEL be more effective if I overuse it?
No. Do not overuse this medicine. If you use more, you will not get rid of acne quicker. Instead, it may make your skin more irritated and red. Therefore, only apply the quantity mentioned by your doctor.
What are the side effects of using AB NEXT GEL?
AB NEXT GEL is generally safe with limited or no side effects. However, you may experience skin dryness, redness or irritation after applying this medicine. Contact your doctor if it troubles you.
What is the use of AB NEXT GEL?
AB NEXT GEL is used in the treatment of acne.
How AB NEXT GEL works?
AB NEXT GEL prevents the accumulation of excess sebum (natural oil produced by the skin) and dead skin cells on the hair follicles of the skin. It also reduces inflammation on the skin and improves skin’s tendency to exfoliate the dead skin cells naturally. It also reduces the number of acne-causing bacteria on the skin which can reduce the further spread of acne.
How to use AB NEXT GEL?
AB NEXT GEL is for external use only. Take the required quantity of the medicine and apply on the affected skin areas. Avoid contact of this medicine with your eyes, ears, nose or any other mucous membranes.
How long does it take for AB NEXT GEL to work?
It may take up to 2-3 weeks for AB NEXT GEL to show improvement in your skin condition. However, this period may vary from person-to-person depending upon the skin condition.
How long should I use AB NEXT GEL?
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. You need to use AB NEXT GEL for the stipulated duration prescribed by your doctor. Failing to do so may not result in adequate response.
What to do if I forgot to apply AB NEXT GEL?
If you forgot to apply AB NEXT GEL, apply it as soon as you remember. However, if it is time for the next application, skip the missed one and apply the next dose. Do not excessively apply AB NEXT GEL to compensate the missed doses.
Is AB NEXT GEL safe?
AB NEXT GEL is safe at doses prescribed by the physician. Therefore, do not alter the dose of AB NEXT GEL without consulting your doctor.
Can I stop using AB NEXT GEL without consulting your doctor?
No. You should not stop using AB NEXT GEL without consulting your doctor as it may reduce its effectiveness. Therefore, apply AB NEXT GEL for the stipulated duration recommended by your doctor to achieve maximum results.
Can AB NEXT GEL be used in pregnant women?
AB NEXT GEL is not recommended for use in pregnant women. Therefore, inform your doctor before using this medicine if you are pregnant, think you may be pregnant or planning to have a baby. If you became pregnant while using this medicine, stop using it and contact your doctor immediately.
1. KD. Tripathi. Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page – 893-894.
2. Bouloc, E. Roo, B. Imko-Walczuk, A. Moga, B. Chadoutaud and B. Dréno. A skincare combined with combination of adapalene and benzoyl peroxide provides a significant adjunctive efficacy and local tolerance benefit in adult women with mild acne. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. July 2017. [Accessed on 8th December 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697630/
3. Laboratoires Galderma. Electronic Medicines Compendium (EMC). [Revised in August 2022] [Accessed on 8th December 2022]. https://www.medicines.org.uk/emc/files/pil.451.pdf
4. Galderma (UK) Ltd. Electronic Medicines Compendium (EMC). [Revised in April 2021] [Accessed on 8th December 2022]. https://www.medicines.org.uk/emc/files/pil.11180.pdf
5. GALDERMA LABORATORIES, L.P. U.S. Food and Drug Administration. [Revised in January 2013] [Accessed on 8th December 2022]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/022320s004lbl.pdf
6. Central Drugs Standard Control Organization. Adapalene 0.1%+Benzoyl peroxide 2.5% gel. October 2008. [Accessed on 8th December 2022]. https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalNewDrugs/dciApprovedfdc.pdf
Written By Srilekha. R, B.Pharm
Last updated on 08 Dec 2022 | 06:31 PM(IST)